Rat ARHGEF7 (Rho Guanine Nucleotide Exchange Factor 7) Sandwich ELISA Kit (STJE0007310)

Rat ARHGEF7 (Rho Guanine Nucleotide Exchange Factor 7) Sandwich ELISA Kit (STJE0007310)

SKU:
STJE0007310
£451.50 - £629.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :This ARHGEF7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates or other biological fluids..
Applications:ELISA
Reactivity:Rat
Sensitivity:0.064ng/mL
Detection Limit:0.156-10ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:4.5 hrs
Gene Symbol:Arhgef7
Gene ID:114559
Uniprot ID:ARHG7_RAT
Sample Type:tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylated on Ser-516 by CaMK1.enhancement of GEF activity and downstream activation of RAC1. Phosphorylated by PTK2/FAK1.this promotes interaction with RAC1.
Function Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Protein Name Rho Guanine Nucleotide Exchange Factor 7
Beta-Pix
Pak-Interacting Exchange Factor Beta
Database Links Reactome: R-RNO-182971
Reactome: -RNO-193648
Reactome: -RNO-3928664
Reactome: -RNO-416482
Reactome: -RNO-8980692
Reactome: -RNO-9013149
Reactome: -RNO-9013406
Reactome: -RNO-9013420
Reactome: -RNO-9013424
Cellular Localisation Cell Junction
Focal Adhesion
Cell Projection
Ruffle
Cytoplasm
Cell Cortex
Lamellipodium
Detected At Cell Adhesions
A Small Proportion Is Detected At Focal Adhesions
Alternative ELISA Names Rho Guanine Nucleotide Exchange Factor 7 ELISA kit
Beta-Pix ELISA kit
Pak-Interacting Exchange Factor Beta ELISA kit
Arhgef7 ELISA kit
Pak3bp ELISA kit
Pixb ELISA kit
output

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJE0007308 Human ARHGEF7 (Rho Guanine Nucleotide Exchange Factor 7) Sandwich ELISA Kit (STJE0007308) Human ELISA
STJE0007309 Mouse ARHGEF7 (Rho Guanine Nucleotide Exchange Factor 7) Sandwich ELISA Kit (STJE0007309) Mouse ELISA
STJE0013686 Rat ARHGEF7 (Rho Guanine Nucleotide Exchange Factor 7) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013686) Rat ELISA
STJE0013684 Human ARHGEF7 (Rho Guanine Nucleotide Exchange Factor 7) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013684) Human ELISA
STJE0013685 Mouse ARHGEF7 (Rho Guanine Nucleotide Exchange Factor 7) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013685) Mouse ELISA

Related Products

!