Rat AGTR1 (Angiotensin II Receptor 1) Sandwich ELISA Kit (STJE0007006)
SPECIFICATIONS
General Information
| Short Description | This AGTR1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 0.053ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Agtr1 |
| Gene ID | 24180 |
| Uniprot ID | AGTRA_RAT |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Is expressed in the liver, kidney, aorta, lung, uterus, ovary, spleen, heart, adrenal gland, and vascular smooth muscle cell. |
| Post Translational Modifications | C-terminal Ser or Thr residues may be phosphorylated. |
| Function | Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. |
| Protein Name | Type-1 Angiotensin Ii Receptor AAngiotensin Ii Type-1 Receptor AAt1 Receptor A |
| Database Links | Reactome: R-RNO-375276Reactome: -RNO-416476Reactome: -RNO-8856825Reactome: -RNO-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Type-1 Angiotensin Ii Receptor A ELISA kitAngiotensin Ii Type-1 Receptor A ELISA kitAt1 Receptor A ELISA kitAgtr1 ELISA kitAgtr1a ELISA kitAt1a ELISA kit |
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Information sourced from Uniprot.org