Tissue Specificity | Detected in testis (at protein level). Preferentially expressed in testis. |
Post Translational Modifications | Cleavage may occur to generate the active 48 kDa form. |
Function | Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. |
Protein Name | Adenylate Cyclase Type 10Germ Cell Soluble Adenylyl CyclaseSacTesticular Soluble Adenylyl Cyclase |
Database Links | Reactome: R-RNO-5610787 |
Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPerinuclear RegionNucleusCell ProjectionCiliumMitochondrionDistributed To Subcellular Compartments Containing Camp TargetsFound As A Plasma Membrane-Associated ProteinProtein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin |
Alternative ELISA Names | Adenylate Cyclase Type 10 ELISA kitGerm Cell Soluble Adenylyl Cyclase ELISA kitSac ELISA kitTesticular Soluble Adenylyl Cyclase ELISA kitAdcy10 ELISA kitSac ELISA kit |
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Information sourced from Uniprot.org