Quiescin Q6 Blocking Peptide peptide (STJ504843)
SPECIFICATIONS
ImmunogenSynthetic peptide corresponding to unique amino acid sequence on human QSOX1 protein.
General Information
| Short Description | Quiescin Q6 Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | QSOX1 |
| Gene ID | 5768 |
| Uniprot ID | QSOX1_HUMAN |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequence on human QSOX1 protein. |
Additional Info
| Tissue Specificity | Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney. |
| Post Translational Modifications | N-glycosylated. O-glycosylated on Thr and Ser residues. |
| Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration. |
| Peptide Name | Sulfhydryl Oxidase 1HqsoxQuiescin Q6 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275 |
| Cellular Localisation | Isoform 1: Golgi Apparatus MembraneSingle-Pass Membrane ProteinSecretedA Small Proportion Is SecretedProbably Via A Proteolytic Cleavage That Removes The Membrane AnchorIsoform 2: SecretedFound In The Extracellular Medium Of Quiescent Cells But Is Not Found In Proliferating Cells |
| Alternative Peptide Names | Sulfhydryl Oxidase 1 proteinHqsox proteinQuiescin Q6 proteinQSOX1 proteinQSCN6 proteinUNQ2520 proteinPRO6013 protein |
Information sourced from Uniprot.org