PREX2 Positive Control for STJ502653 peptide (STJ504800)

Name: PREX2 Positive Control for STJ502653 peptide (STJ504800)
SKU: STJ504800-5
Price: 370.2 EUR
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

STJ504800-5

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	PREX2 Positive Control for STJ502653 is synthetically produced from the sequence and is suitable for use in western blot applications.
Applications	WB
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	WB: 1:500-1:750
Formulation	Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	PREX2
Gene ID	80243
Uniprot ID	PREX2_HUMAN
Specificity	This is positive control is recommended for use in combination with PREX2 antibody STJ502653.

Tissue Specificity	Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart.
Function	Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
Peptide Name	Phosphatidylinositol 3 -4 -5-Trisphosphate-Dependent Rac Exchanger 2 Protein P-Rex2 Ptdins(3 -4 -5-Dependent Rac Exchanger 2 Dep Domain-Containing Protein 2
Database Links	Reactome: R-HSA-8948751 Reactome: R-HSA-8980692 Reactome: R-HSA-9013148 Reactome: R-HSA-9013149
Alternative Peptide Names	Phosphatidylinositol 3 -4 -5-Trisphosphate-Dependent Rac Exchanger 2 Protein protein P-Rex2 protein Ptdins(3 -4 -5-Dependent Rac Exchanger 2 protein Dep Domain-Containing Protein 2 protein PREX2 protein DEPDC2 protein

Information sourced from Uniprot.org