| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | PP2A-delta Positive Control for STJ505952 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | PPP2R5D |
| Gene ID: | 5528 |
| Uniprot ID: | 2A5D_HUMAN |
| Specificity: | This is positive control is recommended for use in combination with PP2A-delta antibody STJ505952. |
| Immunogen: | Purified Serine/Threonine-Protein Phosphatase 2A B56-Delta subunit. |
| Tissue Specificity | Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain. |
| Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
| Peptide Name | Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Delta Isoform Pp2a B Subunit Isoform B'-Delta Pp2a B Subunit Isoform B56-Delta Pp2a B Subunit Isoform Pr61-Delta Pp2a B Subunit Isoform R5-Delta |
| Database Links | Reactome: R-HSA-141444 Reactome: R-HSA-163685 Reactome: R-HSA-163767 Reactome: R-HSA-180024 Reactome: R-HSA-195253 Reactome: R-HSA-196299 Reactome: R-HSA-198753 Reactome: R-HSA-202670 Reactome: R-HSA-2467813 Reactome: R-HSA-2500257 Reactome: R-HSA-389513 Reactome: R-HSA-432142 Reactome: R-HSA-4641262 Reactome: R-HSA-5339716 Reactome: R-HSA-5358747 Reactome: R-HSA-5358749 Reactome: R-HSA-5358751 Reactome: R-HSA-5358752 Reactome: R-HSA-5467337 Reactome: R-HSA-5467340 Reactome: R-HSA-5467348 Reactome: R-HSA-5663220 Reactome: R-HSA-5673000 Reactome: R-HSA-5675221 Reactome: R-HSA-6811558 Reactome: R-HSA-68877 Reactome: R-HSA-9634600 Reactome: R-HSA-9648025 |
| Cellular Localisation | Cytoplasm Nucleus Nuclear In Interphase Nuclear During Mitosis |
| Alternative Peptide Names | Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Delta Isoform protein Pp2a B Subunit Isoform B'-Delta protein Pp2a B Subunit Isoform B56-Delta protein Pp2a B Subunit Isoform Pr61-Delta protein Pp2a B Subunit Isoform R5-Delta protein PPP2R5D protein |
Information sourced from Uniprot.org