POMT1 Positive Control for STJ502579 peptide (STJ504764)
SPECIFICATIONS
General Information
| Short Description | POMT1 Positive Control for STJ502579 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | POMT1 |
| Gene ID | 10585 |
| Uniprot ID | POMT1_HUMAN |
| Specificity | This is positive control is recommended for use in combination with POMT1 antibody STJ502579. |
Additional Info
| Tissue Specificity | Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver. |
| Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. |
| Peptide Name | Protein O-Mannosyl-Transferase 1Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 |
| Database Links | Reactome: R-HSA-5083629Reactome: R-HSA-5083633Reactome: R-HSA-5173105 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Protein O-Mannosyl-Transferase 1 proteinDolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 proteinPOMT1 protein |
Information sourced from Uniprot.org