POMT1 Blocking Peptide for STJ502580 peptide (STJ504763)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 400-460 on human POMT1 protein.
General Information
| Short Description | POMT1 Blocking Peptide for STJ502580 is synthetically produced from the 400-460 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | POMT1 |
| Gene ID | 10585 |
| Uniprot ID | POMT1_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 400-460 on human POMT1 protein. |
| Immunogen Region | 400-460 |
| Specificity | This blocking peptide is recommended for use in combination with POMT1 antibody, STJ502580 |
Additional Info
| Tissue Specificity | Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver. |
| Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. |
| Peptide Name | Protein O-Mannosyl-Transferase 1Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 |
| Database Links | Reactome: R-HSA-5083629Reactome: R-HSA-5083633Reactome: R-HSA-5173105 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Protein O-Mannosyl-Transferase 1 proteinDolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 proteinPOMT1 protein |
Information sourced from Uniprot.org