Phospholipase A2 Positive Control peptide (Phospho) (STJ504743)

SKU:
STJ504743-5

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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Phospho-Phospholipase A2 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PLAA
Gene ID: 9373
Uniprot ID: PLAP_HUMAN
Function Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis.
Peptide Name Phospholipase A-2-Activating Protein
Pla2p
Plap
Cellular Localisation Nucleus
Cytoplasm
Synapse
Recruited To Damaged Lysosomes Decorated With K48-Linked Ubiquitin Chains
Alternative Peptide Names Phospholipase A-2-Activating Protein protein
Pla2p protein
Plap protein
PLAA protein
PLAP protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance