PGCD Positive Control for STJ502462 peptide (STJ504705)

SKU:
STJ504705-5

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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: PGCD Positive Control for STJ502462 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Gucy2d
Gene ID: 113911
Uniprot ID: GUC2D_RAT
Specificity: This is positive control is recommended for use in combination with PGCD antibody STJ502462.
Tissue Specificity Specifically expressed in a subpopulation of olfactory sensory neurons. Expressed in the cilia of the olfactory epithelium.
Function Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference.
Peptide Name Guanylate Cyclase 2d
Guanylate Cyclase - Olfactory
One-Gc
Olfactory Guanylyl Cyclase Gc-D
Gc-D
Cellular Localisation Cell Projection
Cilium Membrane
Single-Pass Type I Membrane Protein
Colocalized With Ncald At The Apical Region Of The Cilia
Coexpresses With Pde2
Alternative Peptide Names Guanylate Cyclase 2d protein
Guanylate Cyclase - Olfactory protein
One-Gc protein
Olfactory Guanylyl Cyclase Gc-D protein
Gc-D protein
Gucy2d protein
Gucy2e protein

Information sourced from Uniprot.org

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