PGCB Positive Control peptide (STJ504701)
SPECIFICATIONS
General Information
| Short Description | PGCB Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NPR2 |
| Gene ID | 4882 |
| Uniprot ID | ANPRB_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated. |
| Function | Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. |
| Peptide Name | Atrial Natriuretic Peptide Receptor 2Atrial Natriuretic Peptide Receptor Type BAnp-BAnpr-BNpr-BGuanylate Cyclase BGc-B |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Peptide Names | Atrial Natriuretic Peptide Receptor 2 proteinAtrial Natriuretic Peptide Receptor Type B proteinAnp-B proteinAnpr-B proteinNpr-B proteinGuanylate Cyclase B proteinGc-B proteinNPR2 proteinANPRB protein |
Information sourced from Uniprot.org