PGCB Blocking Peptide peptide (STJ504700)
SPECIFICATIONS
ImmunogenSynthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase B protein.
General Information
| Short Description | PGCB Blocking Peptide is synthetically produced from the C-Term sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NPR2 |
| Gene ID | 4882 |
| Uniprot ID | ANPRB_HUMAN |
| Immunogen | Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase B protein. |
| Immunogen Region | C-Term |
Additional Info
| Post Translational Modifications | Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated. |
| Function | Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. |
| Peptide Name | Atrial Natriuretic Peptide Receptor 2Atrial Natriuretic Peptide Receptor Type BAnp-BAnpr-BNpr-BGuanylate Cyclase BGc-B |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Peptide Names | Atrial Natriuretic Peptide Receptor 2 proteinAtrial Natriuretic Peptide Receptor Type B proteinAnp-B proteinAnpr-B proteinNpr-B proteinGuanylate Cyclase B proteinGc-B proteinNPR2 proteinANPRB protein |
Information sourced from Uniprot.org