PGCA Positive Control for STJ502628 peptide (STJ504699)
SPECIFICATIONS
General Information
| Short Description | PGCA Positive Control for STJ502628 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NPR1 |
| Gene ID | 4881 |
| Uniprot ID | ANPRA_HUMAN |
| Specificity | This is positive control is recommended for use in combination with PGCA antibody STJ502628. |
Additional Info
| Post Translational Modifications | Phosphorylation of the protein kinase-like domain is required for full activation by ANP. |
| Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. |
| Peptide Name | Atrial Natriuretic Peptide Receptor 1Atrial Natriuretic Peptide Receptor Type AAnp-AAnpr-ANpr-AGuanylate Cyclase AGc-A |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Peptide Names | Atrial Natriuretic Peptide Receptor 1 proteinAtrial Natriuretic Peptide Receptor Type A proteinAnp-A proteinAnpr-A proteinNpr-A proteinGuanylate Cyclase A proteinGc-A proteinNPR1 proteinANPRA protein |
Information sourced from Uniprot.org