PGCA Blocking Peptide peptide (STJ504698)
SPECIFICATIONS
ImmunogenSynthetic peptide corresponding to C terminal amino acids 1042-1057 of Human PGCA. Seqence: VRTYWLLGERGCSTRG
General Information
| Short Description | PGCA Blocking Peptide is synthetically produced from the 1042-1057 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NPR1 |
| Gene ID | 4881 |
| Uniprot ID | ANPRA_HUMAN |
| Immunogen | Synthetic peptide corresponding to C terminal amino acids 1042-1057 of Human PGCA. Seqence: VRTYWLLGERGCSTRG |
| Immunogen Region | 1042-1057 |
Additional Info
| Post Translational Modifications | Phosphorylation of the protein kinase-like domain is required for full activation by ANP. |
| Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. |
| Peptide Name | Atrial Natriuretic Peptide Receptor 1Atrial Natriuretic Peptide Receptor Type AAnp-AAnpr-ANpr-AGuanylate Cyclase AGc-A |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Peptide Names | Atrial Natriuretic Peptide Receptor 1 proteinAtrial Natriuretic Peptide Receptor Type A proteinAnp-A proteinAnpr-A proteinNpr-A proteinGuanylate Cyclase A proteinGc-A proteinNPR1 proteinANPRA protein |
Information sourced from Uniprot.org