PDE6 Beta Positive Control peptide (STJ504661)
SPECIFICATIONS
General Information
| Short Description | PDE6 Beta Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PDE6B |
| Gene ID | 5158 |
| Uniprot ID | PDE6B_HUMAN |
Additional Info
| Function | Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. Necessary for the formation of a functional phosphodiesterase holoenzyme. Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock. May participate in processes of transmission and amplification of the visual signal. |
| Peptide Name | Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit BetaGmp-Pde Beta |
| Database Links | Reactome: R-HSA-2485179Reactome: R-HSA-2514859Reactome: R-HSA-4086398 |
| Cellular Localisation | MembraneLipid-AnchorCell ProjectionCiliumPhotoreceptor Outer Segment |
| Alternative Peptide Names | Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Beta proteinGmp-Pde Beta proteinPDE6B proteinPDEB protein |
Information sourced from Uniprot.org