| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
PDE6 Beta Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
PDE6B |
| Gene ID: |
5158 |
| Uniprot ID: |
PDE6B_HUMAN |
| Immunogen: |
Synthetic cyclic petide common to all PDE6 Beta variants |
| Function | Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. Necessary for the formation of a functional phosphodiesterase holoenzyme. Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock. May participate in processes of transmission and amplification of the visual signal. |
| Peptide Name | Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit BetaGmp-Pde Beta |
| Database Links | Reactome: R-HSA-2485179Reactome: R-HSA-2514859Reactome: R-HSA-4086398 |
| Cellular Localisation | MembraneLipid-AnchorCell ProjectionCiliumPhotoreceptor Outer Segment |
| Alternative Peptide Names | Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Beta proteinGmp-Pde Beta proteinPDE6B proteinPDEB protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
