PDE6 Beta Blocking Peptide peptide (STJ504660)
SPECIFICATIONS
ImmunogenSynthetic cyclic petide common to all PDE6 Beta variants
General Information
| Short Description | PDE6 Beta Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PDE6B |
| Gene ID | 5158 |
| Uniprot ID | PDE6B_HUMAN |
| Immunogen | Synthetic cyclic petide common to all PDE6 Beta variants |
Additional Info
| Function | Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. Necessary for the formation of a functional phosphodiesterase holoenzyme. Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock. May participate in processes of transmission and amplification of the visual signal. |
| Peptide Name | Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit BetaGmp-Pde Beta |
| Database Links | Reactome: R-HSA-2485179Reactome: R-HSA-2514859Reactome: R-HSA-4086398 |
| Cellular Localisation | MembraneLipid-AnchorCell ProjectionCiliumPhotoreceptor Outer Segment |
| Alternative Peptide Names | Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Beta proteinGmp-Pde Beta proteinPDE6B proteinPDEB protein |
Information sourced from Uniprot.org