PDE5A Blocking Peptide for STJ502354 peptide (STJ504659)

SKU:
STJ504659-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: PDE5A Blocking Peptide for STJ502354 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PDE5A
Gene ID: 8654
Uniprot ID: PDE5A_HUMAN
Specificity: This blocking peptide is recommended for use in combination with PDE5A antibody, STJ502354
Immunogen: Recombinant protein common to all PDE5A variants corresponding to human PDE5A protein.
Tissue Specificity Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung.
Post Translational Modifications Phosphorylation is regulated by binding of cGMP to the two allosteric sites. Phosphorylation by PRKG1 leads to its activation.
Function Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide-generated cGMP.
Peptide Name Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase
Cgmp-Binding Cgmp-Specific Phosphodiesterase
Cgb-Pde
Database Links Reactome: R-HSA-418457
Reactome: R-HSA-445355
Reactome: R-HSA-9013422
Alternative Peptide Names Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase protein
Cgmp-Binding Cgmp-Specific Phosphodiesterase protein
Cgb-Pde protein
PDE5A protein
PDE5 protein

Information sourced from Uniprot.org

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