PDE4D7 Positive Control for STJ502342 peptide (STJ504652)
SPECIFICATIONS
General Information
| Short Description | PDE4D7 Positive Control for STJ502342 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Pde4d |
| Gene ID | 238871 |
| Uniprot ID | PDE4D_MOUSE |
| Specificity | This is positive control is recommended for use in combination with PDE4D7 antibody STJ502342. |
Additional Info
| Tissue Specificity | Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis. |
| Post Translational Modifications | Sumoylation of long isoforms by PIAS4 augments their activation by PKA phosphorylation and represses their inhibition by ERK phosphorylation. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. |
| Peptide Name | 3' -5'-Cyclic-Amp Phosphodiesterase 4dDpde3Camp-Specific Phosphodiesterase 4d |
| Database Links | Reactome: R-MMU-180024Reactome: -MMU-418555 |
| Cellular Localisation | CytoplasmMembraneCytoskeletonMicrotubule Organizing CenterCentrosomeApical Cell MembraneColocalized With Shank2 To The Apical Membrane Of Colonic Crypt CellsFound In The Soluble FractionAssociated With MembranesAnd Associated With The Cytoskeleton And The Centrosome |
| Alternative Peptide Names | 3' -5'-Cyclic-Amp Phosphodiesterase 4d proteinDpde3 proteinCamp-Specific Phosphodiesterase 4d proteinPde4d protein |
Information sourced from Uniprot.org