PDE4B2 Positive Control peptide (STJ504633)

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STJ504633-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : PDE4B2 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:750
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PDE4B
Gene ID: 5142
Uniprot ID: PDE4B_HUMAN
Tissue Specificity Expressed in brain, heart, lung and skeletal muscle. Expressed in white blood cells. Isoform PDE4B5: Brain-specific isoform.
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Peptide Name 3' -5'-Cyclic-Amp Phosphodiesterase 4b
Dpde4
Pde32
Camp-Specific Phosphodiesterase 4b
Database Links Reactome: R-HSA-180024 Q07343-3
Cellular Localisation Isoform Pde4b5: Cytoplasm
Cell Membrane
Alternative Peptide Names 3' -5'-Cyclic-Amp Phosphodiesterase 4b protein
Dpde4 protein
Pde32 protein
Camp-Specific Phosphodiesterase 4b protein
PDE4B protein
DPDE4 protein

Information sourced from Uniprot.org

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