PDE4B Positive Control for STJ502321 peptide (STJ505275)
SPECIFICATIONS
General Information
| Short Description | PDE4B Positive Control for STJ502321 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500-1:1, 000 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PDE4B |
| Gene ID | 5142 |
| Uniprot ID | PDE4B_HUMAN |
| Specificity | This is positive control is recommended for use in combination with PDE4B antibody STJ502321. |
Additional Info
| Tissue Specificity | Expressed in brain, heart, lung and skeletal muscle. Expressed in white blood cells. Isoform PDE4B5: Brain-specific isoform. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
| Peptide Name | 3' -5'-Cyclic-Amp Phosphodiesterase 4bDpde4Pde32Camp-Specific Phosphodiesterase 4b |
| Database Links | Reactome: R-HSA-180024 Q07343-3 |
| Cellular Localisation | Isoform Pde4b5: CytoplasmCell Membrane |
| Alternative Peptide Names | 3' -5'-Cyclic-Amp Phosphodiesterase 4b proteinDpde4 proteinPde32 proteinCamp-Specific Phosphodiesterase 4b proteinPDE4B proteinDPDE4 protein |
Information sourced from Uniprot.org