PDE4B Blocking Peptide for STJ502301 peptide (STJ505274)
SPECIFICATIONS
ImmunogenSynthetic peptide common to all PDE4B subtypes taken near N-terminal
General Information
| Short Description | PDE4B Blocking Peptide for STJ502301 is synthetically produced from the N-Term sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PDE4B |
| Gene ID | 5142 |
| Uniprot ID | PDE4B_HUMAN |
| Immunogen | Synthetic peptide common to all PDE4B subtypes taken near N-terminal |
| Immunogen Region | N-Term |
| Specificity | This blocking peptide is recommended for use in combination with PDE4B antibody, STJ502301 |
Additional Info
| Tissue Specificity | Expressed in brain, heart, lung and skeletal muscle. Expressed in white blood cells. Isoform PDE4B5: Brain-specific isoform. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
| Peptide Name | 3' -5'-Cyclic-Amp Phosphodiesterase 4bDpde4Pde32Camp-Specific Phosphodiesterase 4b |
| Database Links | Reactome: R-HSA-180024 Q07343-3 |
| Cellular Localisation | Isoform Pde4b5: CytoplasmCell Membrane |
| Alternative Peptide Names | 3' -5'-Cyclic-Amp Phosphodiesterase 4b proteinDpde4 proteinPde32 proteinCamp-Specific Phosphodiesterase 4b proteinPDE4B proteinDPDE4 protein |
Information sourced from Uniprot.org