PDE11A Positive Control peptide (Phospho) (S163) (STJ505879)
SPECIFICATIONS
General Information
| Short Description | Phospho-PDE11A Positive Control is synthetically produced from the sequence about the S163 and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Pde11a |
| Gene ID | 140928 |
| Uniprot ID | PDE11_RAT |
Additional Info
| Tissue Specificity | Isoform 1 is expressed in brain, heart, kidney and liver, but not in prostate. Isoform 2 is specifically expressed in testis. Isoform 3 is expressed in various tissues including brain, lung, skeletal muscle, spleen, testis and prostate. |
| Function | Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively. |
| Peptide Name | Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11aCamp And Cgmp Phosphodiesterase 11a |
| Database Links | Reactome: R-RNO-418457Reactome: -RNO-418555 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Peptide Names | Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11a proteinCamp And Cgmp Phosphodiesterase 11a proteinPde11a protein |
Information sourced from Uniprot.org