PARD6B Positive Control for STJ506126 peptide (STJ505848)
SPECIFICATIONS
General Information
| Short Description | PARD6B Positive Control for STJ506126 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PARD6B |
| Gene ID | 84612 |
| Uniprot ID | PAR6B_HUMAN |
| Specificity | This is positive control is recommended for use in combination with PARD6B antibody STJ506126. |
Additional Info
| Tissue Specificity | Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues. |
| Function | Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. |
| Peptide Name | Partitioning Defective 6 Homolog BetaPar-6 BetaPar-6b |
| Database Links | Reactome: R-HSA-420029Reactome: R-HSA-9013424 |
| Cellular Localisation | CytoplasmCell MembraneCell JunctionTight Junction |
| Alternative Peptide Names | Partitioning Defective 6 Homolog Beta proteinPar-6 Beta proteinPar-6b proteinPARD6B proteinPAR6B protein |
Information sourced from Uniprot.org