PARD6B Blocking Peptide for STJ506140 peptide (STJ505862)

SKU:
STJ505862-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: PARD6B Blocking Peptide for STJ506140 is synthetically produced from the 340-372 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PARD6B
Gene ID: 84612
Uniprot ID: PAR6B_HUMAN
Immunogen Region: 340-372
Specificity: This blocking peptide is recommended for use in combination with PARD6B antibody, STJ506140
Immunogen: Synthetic peptide corresponding to amino acids within region 340-372 on human Partitioning Defective 6 homolog beta.
Tissue Specificity Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
Function Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Peptide Name Partitioning Defective 6 Homolog Beta
Par-6 Beta
Par-6b
Database Links Reactome: R-HSA-420029
Reactome: R-HSA-9013424
Cellular Localisation Cytoplasm
Cell Membrane
Cell Junction
Tight Junction
Alternative Peptide Names Partitioning Defective 6 Homolog Beta protein
Par-6 Beta protein
Par-6b protein
PARD6B protein
PAR6B protein

Information sourced from Uniprot.org

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