p27 KIP1 Positive Control peptide (Phospho) (STJ504738)

SPECIFICATIONS
STJ504738-5
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General Information

Short DescriptionPhospho-p27 KIP1 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
ApplicationsWB
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeWB: 1:250
Storage InstructionStore at-20°C for long term storage. Avoid freeze-thaw cycles.

Target Information

Additional Info

Background Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E-and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Information sourced from Uniprot.org

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