Native Human F8/Coagulation factor VIII protein (Native) (STJP013026)
SPECIFICATIONS
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Native-Native Human F8/Coagulation factor VIII-protein was developed from. For use in research applications. |
| Applications | ELISA/WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.2. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | F8 |
| Gene ID | 2157 |
| Uniprot ID | FA8_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Full length |
Additional Info
| Function | Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa. |
| Protein Name | Coagulation Factor ViiiAntihemophilic FactorAhfProcoagulant Component Cleaved Into - Factor Viiia Heavy Chain - 200 Kda Isoform - Factor Viiia Heavy Chain - 92 Kda Isoform - Factor Viii B Chain - Factor Viiia Light Chain |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-140837Reactome: R-HSA-140875Reactome: R-HSA-163841Reactome: R-HSA-204005Reactome: R-HSA-5694530Reactome: R-HSA-9672383Reactome: R-HSA-9672387Reactome: R-HSA-9672391Reactome: R-HSA-9672393Reactome: R-HSA-9672395Reactome: R-HSA-9672396Reactome: R-HSA-9672397Reactome: R-HSA-9673202Reactome: R-HSA-9674519 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Protein Names | Coagulation Factor Viii proteinAntihemophilic Factor proteinAhf proteinProcoagulant Component Cleaved Into - Factor Viiia Heavy Chain - 200 Kda Isoform - Factor Viiia Heavy Chain - 92 Kda Isoform - Factor Viii B Chain - Factor Viiia Light Chain proteinF8 proteinF8C protein |
Information sourced from Uniprot.org