Myoregulin Blocking Peptide peptide (STJ505486)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 1-50 on human Myoregulin protein.
General Information
| Short Description | Myoregulin Blocking Peptide is synthetically produced from the 1-50 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | MRLN |
| Gene ID | 100507027 |
| Uniprot ID | MLN_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 1-50 on human Myoregulin protein. |
| Immunogen Region | 1-50 |
Additional Info
| Function | Inhibits the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+), thereby acting as a key regulator of skeletal muscle activity. Its high expression in adult skeletal muscle, suggests that it constitutes the predominant regulator of ATP2A1/SERCA1 in adult skeletal muscle. Also inhibits the activity of ATP2A2/SERCA2 and ATP2A3/SERCA3. |
| Peptide Name | Myoregulin |
| Cellular Localisation | Sarcoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative Peptide Names | Myoregulin proteinMRLN proteinMLN protein |
Information sourced from Uniprot.org