| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
MTAP Blocking Peptide for STJ503533 is synthetically produced from the 233-283 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
MTAP |
| Gene ID: |
4507 |
| Uniprot ID: |
MTAP_HUMAN |
| Immunogen Region: |
233-283 |
| Specificity: |
This blocking peptide is recommended for use in combination with MTAP antibody, STJ503533 |
| Immunogen: |
Synthetic peptide taken within amino acid region 233-283 on human methylthioadenosine phosphorylase protein. |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. |
| Peptide Name | S-Methyl-5'-Thioadenosine Phosphorylase5'-Methylthioadenosine PhosphorylaseMta PhosphorylaseMtapMtapase |
| Database Links | Reactome: R-HSA-1237112Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Peptide Names | S-Methyl-5'-Thioadenosine Phosphorylase protein5'-Methylthioadenosine Phosphorylase proteinMta Phosphorylase proteinMtap proteinMtapase proteinMTAP proteinMSAP protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
