MSF Blocking Peptide is synthetically produced from the 1-60 sequence and is suitable for use in western blot applications.
Applications
Immunodepletion/Immunocompetition
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Formulation
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction
Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles.
Synthetic peptide taken within amino acid region 1-60 on SEPT9 protein.
Immunogen Region
1-60
Additional Info
Tissue Specificity
Widely expressed. Isoforms are differentially expressed in testes, kidney, liver heart, spleen, brain, peripheral blood leukocytes, skeletal muscle and kidney. Specific isoforms appear to demonstrate tissue specificity. Isoform 5 is the most highly expressed in fetal tissue. Isoform 1 is detected in all tissues except the brain and thymus, while isoform 2, isoform 3, and isoform 4 are detected at low levels in approximately half of the fetal tissues.
Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
CytoplasmCytoskeletonIn An Epithelial Cell LineConcentrates At Cell-Cell Contact AreasAfter Tgf-Beta1 Treatment And Induction Of Epithelial To Mesenchymal TransitionColocalizes Partly With Actin Stress FibersDuring Bacterial InfectionDisplays A Collar Shape Structure Next To Actin At The Pole Of Invading Bacteria
Alternative Peptide Names
Septin-9 proteinMll Septin-Like Fusion Protein Msf-A proteinMll Septin-Like Fusion Protein proteinOvarian/Breast Septin proteinOv/Br Septin proteinSeptin D1 proteinSEPTIN9 proteinKIAA0991 proteinMSF proteinSEPT9 protein
