Mouse WFS1 (Wolfram Syndrome Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019476)

SPECIFICATIONS
STJE0019476
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General Information

Short DescriptionThis WFS1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids..
ApplicationsELISA
ReactivityMouse
Sensitivity0.133ng/mL
Detection Limit0.312-20ng/mL
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Storage InstructionThe whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time3 hrs

Target Information

Gene SymbolWfs1
Gene ID22393
Uniprot IDWFS1_MOUSE
Immunogen RegionReady-To-Use
Sample Typetissue homogenates or other biological fluids.

Additional Info

Tissue Specificity Highly expressed in the developing lens.
Post Translational Modifications
Function Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store. Negatively regulates the ER stress response and positively regulates the stability of V-ATPase subunits ATP6V1A and ATP1B1 by preventing their degradation through an unknown proteasome-independent mechanism.
Protein Name Wolframin
Database Links Reactome: R-MMU-381426
Reactome: -MMU-8957275
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle
Secretory Vesicle
Co-Localizes With Atp6v1a In The Secretory Granules In Neuroblastoma Cell Lines
Alternative ELISA Names Wolframin ELISA kit
Wfs1 ELISA kit
output

Information sourced from Uniprot.org

Citations

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