Mouse VWF (Von Willebrand Factor) Antibody Pair (STJAP00551)
General Information
| Short Description | This VWF antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Sheep/Sheep |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | Vwf |
| Gene ID | 22371 |
| Uniprot ID | VWF_MOUSE |
| Immunogen | Capture immunogen: Natural Mouse VWF protien.Detection Immunogen: Natural Mouse VWF protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Post Translational Modifications | All cysteine residues are involved in intrachain or interchain disulfide bonds. N- and O-glycosylated. |
| Function | Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. |
| Protein Name | Von Willebrand FactorVwf Cleaved Into - Von Willebrand Antigen 2Von Willebrand Antigen Ii |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-140837Reactome: -MMU-216083Reactome: -MMU-354192Reactome: -MMU-354194Reactome: -MMU-372708Reactome: -MMU-430116Reactome: -MMU-5674135Reactome: -MMU-75892Reactome: -MMU-76009 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixLocalized To Storage Granules |
| Alternative Antibody Pair Names | Von Willebrand Factor antibody pairVwf Cleaved Into - Von Willebrand Antigen 2 antibody pairVon Willebrand Antigen Ii antibody pairVwf antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Mouse VWF (Von Willebrand Factor) Antibody Pair (STJAP00551)
This antibody pair detects Von Willebrand Factor (VWF, UniProt Q8CIZ8) and is validated for reactivity against mouse. It is not described as cross-reactive with human or other species based on the provided data.
The capture antibody is supplied unconjugated, while the detection antibody is biotin-conjugated. Both are sheep-derived, purified by antigen affinity, and supplied at 0.5 mg/mL.
This pair is validated for use in ELISA. Suitable sample types include serum, plasma, and other biological fluids from mouse.
Both the capture and detection antibodies were raised against natural mouse VWF protein. Both were also purified by antigen affinity chromatography.
The capture antibody is formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.5. The detection antibody is formulated in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol at pH 7.5. Both components should be stored at -20°C for long-term storage, and freeze-thaw cycles should be avoided.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.