Mouse VEGFB (VEGFB) Antibody Pair (STJAP00837)
General Information
| Short Description | This VEGFB antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R21-2M-3/R67-3O-9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | Vegfb |
| Gene ID | 22340 |
| Uniprot ID | VEGFB_MOUSE |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | Abundantly expressed in heart, brain, kidney and skeletal muscle. |
| Post Translational Modifications | VEGF-B186 is O-glycosylated. |
| Function | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. VEGF-B seems to be required for normal heart function in adult but is not required for proper development of the cardiovascular system either during development or for angiogenesis in adults. |
| Protein Name | Vascular Endothelial Growth Factor BVegf-BVegf-Related FactorVrf |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-194313Reactome: -MMU-195399 |
| Cellular Localisation | SecretedSecreted But Remains Associated To Cells Or To The Extracellular Matrix Unless Released By Heparin |
| Alternative Antibody Pair Names | Vascular Endothelial Growth Factor B antibody pairVegf-B antibody pairVegf-Related Factor antibody pairVrf antibody pairVegfb antibody pairVrf antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Mouse VEGFB (VEGFB) Antibody Pair (STJAP00837)
This antibody pair is designed to detect mouse VEGFB (Vascular Endothelial Growth Factor B), with reactivity confirmed for the mouse species. The relevant UniProt entry for the target is P49766.
This antibody pair has been validated for use in ELISA. It is intended for use as a matched capture and detection pair in sandwich ELISA configurations.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated at 1 mg/mL, formulated in 0.01M PBS at pH 7.2. Clone IDs are R21-2M-3 and R67-3O-9, and both are affinity purified.
Optimal working dilutions for both the capture and detection antibodies are to be determined by the end user. Titration experiments are recommended to establish appropriate concentrations for each specific experimental setup.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquots should be kept at -20°C, and repeated freeze/thaw cycles should be avoided to preserve activity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.