Mouse VEGF-D (Vascular Endothelial Growth Factor D) Antibody Pair (STJAP00543)
SPECIFICATIONS
HostGoat/Goat
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Mouse VEGF-D protien.Detection Immunogen: Recombinant Mouse VEGF-D protien.
General Information
| Short Description | This VEGF-D antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | Vegfd |
| Gene ID | 14205 |
| Uniprot ID | VEGFD_MOUSE |
| Immunogen | Capture immunogen: Recombinant Mouse VEGF-D protien.Detection Immunogen: Recombinant Mouse VEGF-D protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Post Translational Modifications | Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions. |
| Function | Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-3 (Flt4) receptor. |
| Protein Name | Vascular Endothelial Growth Factor DVegf-DC-Fos-Induced Growth FactorFigf |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-194313Reactome: -MMU-195399 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | Vascular Endothelial Growth Factor D antibody pairVegf-D antibody pairC-Fos-Induced Growth Factor antibody pairFigf antibody pairVegfd antibody pairFigf antibody pair |
Information sourced from Uniprot.org