Mouse uPAR protein (Recombinant) (STJP001868)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding Urokinase-type plasminogen activator receptor (LEU24-THR297) including a C-terminal His tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Mouse uPAR-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Target Information
| Gene Symbol | Plaur |
| Gene ID | 18793 |
| Uniprot ID | UPAR_MOUSE |
| Immunogen | Optimized DNA sequence encoding Urokinase-type plasminogen activator receptor (LEU24-THR297) including a C-terminal His tag was expressed in HEK293 cells. NA |
| Immunogen Region | LEU24-THR297 |
Additional Info
| Tissue Specificity | Expressed in angiogenic endothelial cells (at protein level). |
| Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. |
| Protein Name | Urokinase Plasminogen Activator Surface ReceptorU-ParUparCd Antigen Cd87 |
| Database Links | Reactome: R-MMU-162791Reactome: -MMU-6798695Reactome: -MMU-75205 |
| Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorGpi-AnchorIsoform 2: Secreted |
| Alternative Protein Names | Urokinase Plasminogen Activator Surface Receptor proteinU-Par proteinUpar proteinCd Antigen Cd87 proteinPlaur protein |
Information sourced from Uniprot.org