Tissue Specificity | |
Post Translational Modifications | Glycosylated. Sulfated. Sulfation on Tyr-385 plays a role in thyrotropin receptor binding and activation. |
Function | Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. |
Protein Name | Thyrotropin ReceptorThyroid-Stimulating Hormone ReceptorTsh-R |
Database Links | Reactome: R-MMU-375281Reactome: -MMU-418555 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
Alternative ELISA Names | Thyrotropin Receptor ELISA kitThyroid-Stimulating Hormone Receptor ELISA kitTsh-R ELISA kitTshr ELISA kit |
output | |
Information sourced from Uniprot.org