Mouse TRAIL/TNFSF10 (Tumor Necrosis Factor Ligand Superfamily Member 10) Antibody Pair (STJAP00532)
General Information
| Short Description | This TRAIL/TNFSF10 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Rat/Goat |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A or G.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | Tnfsf10 |
| Gene ID | 22035 |
| Uniprot ID | TNF10_MOUSE |
| Immunogen | Capture immunogen: Recombinant Mouse TRAIL/TNFSF10 protien.Detection Immunogen: Recombinant Mouse TRAIL/TNFSF10 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Post Translational Modifications | Tyrosine phosphorylated by PKDCC/VLK. |
| Function | Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 10Tnf-Related Apoptosis-Inducing LigandProtein TrailCd Antigen Cd253 |
| Database Links | Reactome: R-MMU-3371378Reactome: -MMU-5218900Reactome: -MMU-69416Reactome: -MMU-75158 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinSecretedExists Both As Membrane-Bound And Soluble Form |
| Alternative Antibody Pair Names | Tumor Necrosis Factor Ligand Superfamily Member 10 antibody pairTnf-Related Apoptosis-Inducing Ligand antibody pairProtein Trail antibody pairCd Antigen Cd253 antibody pairTnfsf10 antibody pairTrail antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Mouse TRAIL/TNFSF10 (Tumor Necrosis Factor Ligand Superfamily Member 10) Antibody Pair (STJAP00532)
This antibody pair detects mouse TRAIL/TNFSF10 (Tumor Necrosis Factor Ligand Superfamily Member 10), corresponding to UniProt entry P50592. Reactivity is confirmed for mouse samples only.
The capture antibody is unconjugated and supplied in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.5, while the detection antibody is biotinylated and supplied in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol at pH 7.5. Both components are provided at 0.5 mg/mL.
This antibody pair has been validated for ELISA only. It is intended for use with serum, plasma, and other biological fluids.
The capture and detection antibodies were raised in rat and goat, respectively. The capture antibody was purified by Protein A or G, and the detection antibody was purified by antigen affinity.
Both the capture and detection antibodies were raised against recombinant mouse TRAIL/TNFSF10 protein. No specific immunogen region is stated in the product information.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to maintain reagent integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.