Mouse TNFSF12 (Tumor Necrosis Factor Ligand Superfamily, Member 12) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019083)
SPECIFICATIONS
General Information
| Short Description | This TNFSF12 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 31.6pg/mL |
| Detection Limit | 78.1-5000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Tnfsf12 |
| Gene ID | 21944 |
| Uniprot ID | TNF12_MOUSE |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | The soluble form is produced from the membrane form by proteolytic processing. |
| Function | Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 12Tnf-Related Weak Inducer Of ApoptosisTweak Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 12 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 12 - Secreted Form |
| Database Links | Reactome: R-MMU-5668541Reactome: -MMU-5676594 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinTumor Necrosis Factor Ligand Superfamily Member 12Secreted Form: Secreted |
| Alternative ELISA Names | Tumor Necrosis Factor Ligand Superfamily Member 12 ELISA kitTnf-Related Weak Inducer Of Apoptosis ELISA kitTweak Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 12 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 12 - Secreted Form ELISA kitTnfsf12 ELISA kit |
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Information sourced from Uniprot.org