Mouse TNFRSF9/4-1BB/CD137 protein (Recombinant) (C-hFc) (STJP002786)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Mouse TNFRSF9/4-1BB/CD137 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val24-Leu211) of mouse TNFRSF9/4-1BB/CD137 (Accession #NP_001070976.1) fused with a hFc tag at the C-terminus.
General Information
| Short Description | Recombinant-Mouse TNFRSF9/4-1BB/CD137-C-hFc protein was developed in hek293 cells using the region Val24-Leu211. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA. Immobilized Mouse TNFSF9 at 5 Mu g/mL (100 Mu L/well) can bind Mouse TNFRSF9/4-1BB/CD137 with a linear range of 0.005-1.41 ng/mL. |
| Determination Method | <1 EU/Mu g |
Target Information
| Gene Symbol | Tnfrsf9 |
| Gene ID | 21942 |
| Uniprot ID | TNR9_MOUSE |
| Immunogen | Recombinant Mouse TNFRSF9/4-1BB/CD137 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val24-Leu211) of mouse TNFRSF9/4-1BB/CD137 (Accession #NP_001070976.1) fused with a hFc tag at the C-terminus. |
| Immunogen Region | Val24-Leu211 |
| Immunogen Sequence | VQNSCDNCQPGTFCRKYNPV CKSCPPSTFSSIGGQPNCNI CRVCAGYFRFKKFCSSTHNA ECECIEGFHCLGPQCTRCEK DCRPGQELTKQGCKTCSLGT FNDQNGTGVCRPWTNCSLDG RSVLKTGTTEKDVVCGPPVV SFSPSTTISVTPEGGPAFKK TTGAAQEEDACSCRCPQEEE GGGGGYEL |
Additional Info
| Function | Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 94-1bb Ligand ReceptorT-Cell Antigen 4-1bbCd Antigen Cd137 |
| Database Links | Reactome: R-MMU-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 9 protein4-1bb Ligand Receptor proteinT-Cell Antigen 4-1bb proteinCd Antigen Cd137 proteinTnfrsf9 proteinCd137 proteinIla proteinLy63 protein |
Information sourced from Uniprot.org