• Mouse Siglec-3/CD33 protein (Recombinant) (C-His) (STJP001494)

Mouse Siglec-3/CD33 protein (Recombinant) (C-His) (STJP001494)

SKU:
STJP001494

Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse Siglec-3/CD33-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Gene Symbol: Cd33
Gene ID: 12489
Uniprot ID: CD33_MOUSE
Immunogen: Recombinant Mouse Siglec-3/CD33 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp18-Glu240) of mouse Siglec3/CD33 (Accession #NP_001104528.1) fused with a 6×His tag at the C-terminus.
Post Translational Modifications Glycosylated. Phosphorylation is involved in binding to PTPN6 and PTPN11.
Function Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Preferentially binds sialic acid to the short O-linked glycans of certain mucins.
Protein Name Myeloid Cell Surface Antigen Cd33
Sialic Acid-Binding Ig-Like Lectin 3
Siglec-3
Cd Antigen Cd33
Database Links Reactome: R-MMU-198933
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Myeloid Cell Surface Antigen Cd33 protein
Sialic Acid-Binding Ig-Like Lectin 3 protein
Siglec-3 protein
Cd Antigen Cd33 protein
Cd33 protein
Siglec3 protein

Information sourced from Uniprot.org

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