Mouse SELP (Selectin, Platelet) Sandwich ELISA Kit (STJE0007156)
SPECIFICATIONS
General Information
| Short Description | This SELP Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, platelet-poor plasma, tissue homogenates, cell culture supernates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.068ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Selp |
| Gene ID | 20344 |
| Uniprot ID | LYAM3_MOUSE |
| Sample Type | serum, platelet-poor plasma, tissue homogenates, cell culture supernates or other biological fluids. |
Additional Info
| Tissue Specificity | Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface. |
| Post Translational Modifications | |
| Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3). |
| Protein Name | P-SelectinCd62 Antigen-Like Family Member PGranule Membrane Protein 140Gmp-140Leukocyte-Endothelial Cell Adhesion Molecule 3Lecam3Platelet Activation Dependent Granule-External Membrane ProteinPadgemCd Antigen Cd62p |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | P-Selectin ELISA kitCd62 Antigen-Like Family Member P ELISA kitGranule Membrane Protein 140 ELISA kitGmp-140 ELISA kitLeukocyte-Endothelial Cell Adhesion Molecule 3 ELISA kitLecam3 ELISA kitPlatelet Activation Dependent Granule-External Membrane Protein ELISA kitPadgem ELISA kitCd Antigen Cd62p ELISA kitSelp ELISA kitGrmp ELISA kit |
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Information sourced from Uniprot.org