Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3). |
Protein Name | P-SelectinCd62 Antigen-Like Family Member PGranule Membrane Protein 140Gmp-140Leukocyte-Endothelial Cell Adhesion Molecule 3Lecam3Platelet Activation Dependent Granule-External Membrane ProteinPadgemCd Antigen Cd62p |
Database Links | Reactome: R-MMU-114608Reactome: -MMU-202733 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Pair Names | P-Selectin antibody pairCd62 Antigen-Like Family Member P antibody pairGranule Membrane Protein 140 antibody pairGmp-140 antibody pairLeukocyte-Endothelial Cell Adhesion Molecule 3 antibody pairLecam3 antibody pairPlatelet Activation Dependent Granule-External Membrane Protein antibody pairPadgem antibody pairCd Antigen Cd62p antibody pairSelp antibody pairGrmp antibody pair |
Information sourced from Uniprot.org