Mouse PSGL1 (P-Selectin Glycoprotein Ligand 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018094)
SPECIFICATIONS
General Information
| Short Description | This PSGL1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.065ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | SelplgUniprot ID=SELPL_MOUSE" |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | Highly expressed in blood, bone marrow, brain, adipose tissue, spleen, and thymus. Also expressed in heart, kidney, liver, muscle, ovary, and stomach. |
| Post Translational Modifications | Displays complex, core-2, sialylated and fucosylated O-linked oligosaccharides, at least some of which appear to contain poly-N-acetyllactosamine with varying degrees of substitution. Mainly disialylated or neutral forms of the core-2 tetrasaccharide, Galbeta1-->4GlcNAcbeta1-->6(Galbeta1-->3)GalNAcOH. The GlcN:GalN ratio is approximately 2:1 and the Man:Fuc ratio 3:5. Contains about 14% fucose with alpha-1,3 linkage present in two forms: One species is a disialylated, monofucosylated glycan, and the other, a monosialylated, trifucosylated glycan with a polylactosamine backbone. The fucosylated forms carry the Lewis antigen and are important for interaction with selectins and for functioning. No sulfated O-glycans. Some N-glycosylation. |
| Function | A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E- and P-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture. |
| Protein Name | P-Selectin Glycoprotein Ligand 1Psgl-1Selectin P LigandCd Antigen Cd162 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane Protein |
| Alternative ELISA Names | P-Selectin Glycoprotein Ligand 1 ELISA kitPsgl-1 ELISA kitSelectin P Ligand ELISA kitCd Antigen Cd162 ELISA kitSelplg ELISA kitSelp1 ELISA kitSelpl ELISA kit |
| output |
Information sourced from Uniprot.org