Mouse Ntn1 (Netrin 1) Sandwich ELISA Kit (STJE0011129)

SPECIFICATIONS
STJE0011129
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General Information

Short DescriptionThis Ntn1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids..
ApplicationsELISA
ReactivityMouse
Sensitivity5.9pg/mL
Detection Limit15.6-1000pg/mL
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Storage InstructionStore the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time4.5 hrs

Target Information

Gene SymbolNtn1
Gene ID18208
Uniprot IDNET1_MOUSE
Sample Typeserum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Additional Info

Tissue Specificity In the embryo, widely expressed in the developing nervous system and in mesodermal tissues.
Post Translational Modifications
Function Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Involved in dorsal root ganglion axon projection towards the spinal cord. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis.
Protein Name Netrin-1
Database Links
Cellular Localisation Secreted
Cytoplasm
Mainly Secreted
Alternative ELISA Names Netrin-1 ELISA kit
Ntn1 ELISA kit
output

Information sourced from Uniprot.org

Citations

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