Mouse NRG4 (Neuregulin 4) Sandwich ELISA Kit (STJE0011085)
SPECIFICATIONS
General Information
| Short Description | This NRG4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.128ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Nrg4 |
| Gene ID | 83961 |
| Uniprot ID | NRG4_MOUSE |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Highly expressed in pancreas.weakly expressed in muscle. |
| Post Translational Modifications | Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form. Extensive glycosylation precedes the proteolytic cleavage. |
| Function | Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors. |
| Protein Name | Pro-Neuregulin-4 - Membrane-Bound IsoformPro-Nrg4 Cleaved Into - Neuregulin-4Nrg-4 |
| Database Links | |
| Cellular Localisation | Pro-Neuregulin-4Membrane-Bound Isoform: Cell MembraneSingle-Pass Type I Membrane ProteinDoes Not Seem To Be ActiveNeuregulin-4: Secreted |
| Alternative ELISA Names | Pro-Neuregulin-4 - Membrane-Bound Isoform ELISA kitPro-Nrg4 Cleaved Into - Neuregulin-4 ELISA kitNrg-4 ELISA kitNrg4 ELISA kit |
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Information sourced from Uniprot.org