Mouse NEFL (Neurofilament, Light Polypeptide) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017296)
SPECIFICATIONS
General Information
| Short Description | This NEFL Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, cerebrospinal fluid or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 12.5pg/mL |
| Detection Limit | 31.2-2000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Nefl |
| Gene ID | 18039 |
| Uniprot ID | NFL_MOUSE |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma, cerebrospinal fluid or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in the sciatic nerve (at protein level). |
| Post Translational Modifications | O-glycosylated. Phosphorylated in the head and rod regions by the PKC kinase PKN1, leading to the inhibition of polymerization. Ubiquitinated in the presence of TRIM2 and UBE2D1. |
| Function | Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. |
| Protein Name | Neurofilament Light PolypeptideNf-L68 Kda Neurofilament ProteinNeurofilament Triplet L Protein |
| Database Links | Reactome: R-MMU-438066Reactome: -MMU-5673001 |
| Cellular Localisation | Cell ProjectionAxonCytoplasmCytoskeleton |
| Alternative ELISA Names | Neurofilament Light Polypeptide ELISA kitNf-L ELISA kit68 Kda Neurofilament Protein ELISA kitNeurofilament Triplet L Protein ELISA kitNefl ELISA kitNf68 ELISA kitNfl ELISA kit |
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Information sourced from Uniprot.org