Mouse MYL9 protein (Recombinant) (His-Tag) (STJP019157)

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STJP019157
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Short Description :Recombinant-Mouse MYL9-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:Myl9
Gene ID:98932
Uniprot ID:MYL9_MOUSE
Accession Number:NP_742116
Immunogen:Mouse
Immunogen Region:1-172aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMSSKRA KAKTTKKRPQ RATSNVFAMF DQSQIQEFKE AFNMIDQNRD GFIDKEDLHD MLASLGKNPT DEYLEGMMNE APGPINFTMF LTMFGEKLNG TDPEDVIRNA FACFDEEASG FIHEDHLREL LTTMGDRFTD EEVDEMYREA PIDKKGNFNY VEFTRILKHG AKDKDD
Post Translational Modifications Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge. Phosphorylation is required for myotube formation. Phosphorylated by DAPK3.DAPK3-mediated phosphorylation is inhibited by LUZP1.
Function Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. In myoblasts, regulates PIEZO1-dependent cortical actomyosin assembly involved in myotube formation.
Protein Name Myosin Regulatory Light Polypeptide 9
Myosin Regulatory Light Chain 2 - Smooth Muscle Isoform
Myosin Regulatory Light Chain 9
Database Links Reactome: R-MMU-445355
Reactome: -MMU-5627123
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Cortex
Colocalizes With F-Actin
Myh9 And Piezo1 At The Actomyosin Cortex In Myoblasts
Alternative Protein Names Myosin Regulatory Light Polypeptide 9 protein
Myosin Regulatory Light Chain 2 - Smooth Muscle Isoform protein
Myosin Regulatory Light Chain 9 protein
Myl9 protein
Myrl2 protein

Information sourced from Uniprot.org

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