| Short Description : | Recombinant-Mouse Thrombopoietin-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Bioactivity |
| Host: | HEK293 Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity: | Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 range ≤4ng/ml. |
| Gene Symbol: | Thpo |
| Gene ID: | 21832 |
| Uniprot ID: | TPO_MOUSE |
| Accession Number: | NP_033405 |
| Immunogen: | Mouse |
| Immunogen Region: | 22-356aa |
| Immunogen Sequence: | SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKFPNRTSG LLETNFSVTA RTAGPGLLSR LQGFRVKITP GQLNQTSRSP VQISGYLN |
| Tissue Specificity | Found mainly in the liver, kidney and skeletal muscle. |
| Function | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
| Protein Name | ThrombopoietinC-Mpl LigandMlMegakaryocyte Colony-Stimulating FactorMegakaryocyte Growth And Development FactorMgdfMyeloproliferative Leukemia Virus Oncogene Ligand |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Thrombopoietin proteinC-Mpl Ligand proteinMl proteinMegakaryocyte Colony-Stimulating Factor proteinMegakaryocyte Growth And Development Factor proteinMgdf proteinMyeloproliferative Leukemia Virus Oncogene Ligand proteinThpo protein |
Information sourced from Uniprot.org
