Human MYL9 protein (Recombinant) (N-His) (STJP004404)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human MYL9-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | MYL9 |
| Gene ID | 10398 |
| Uniprot ID | MYL9_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg5-Leu163 |
Additional Info
| Post Translational Modifications | Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge. Phosphorylation is required for myotube formation. Phosphorylated by DAPK3.DAPK3-mediated phosphorylation is inhibited by LUZP1. |
| Function | Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation. |
| Protein Name | Myosin Regulatory Light Polypeptide 920 Kda Myosin Light ChainLc20Mlc-2cMyosin RlcMyosin Regulatory Light Chain 2 - Smooth Muscle IsoformMyosin Regulatory Light Chain 9Myosin Regulatory Light Chain Mrlc1 |
| Database Links | Reactome: R-HSA-3928663Reactome: R-HSA-416572Reactome: R-HSA-445355Reactome: R-HSA-5625740Reactome: R-HSA-5625900Reactome: R-HSA-5627117Reactome: R-HSA-5627123Reactome: R-HSA-8936459 |
| Cellular Localisation | CytoplasmCytoskeletonCell CortexColocalizes With F-ActinMyh9 And Piezo1 At The Actomyosin Cortex In Myoblasts |
| Alternative Protein Names | Myosin Regulatory Light Polypeptide 9 protein20 Kda Myosin Light Chain proteinLc20 proteinMlc-2c proteinMyosin Rlc proteinMyosin Regulatory Light Chain 2 - Smooth Muscle Isoform proteinMyosin Regulatory Light Chain 9 proteinMyosin Regulatory Light Chain Mrlc1 proteinMYL9 proteinMLC2 proteinMRLC1 proteinMYRL2 protein |
Information sourced from Uniprot.org