Mouse MTMR9 (Myotubularin Related Protein 9) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017152)
SPECIFICATIONS
General Information
| Short Description | This MTMR9 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.058ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Mtmr9 |
| Gene ID | 210376 |
| Uniprot ID | MTMR9_MOUSE |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Acts as an adapter for myotubularin-related phosphatases. Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5-bisphosphate, and MTMR6 binding affinity for phosphorylated phosphatidylinositols. Positively regulates lipid phosphatase MTMR7 catalytic activity. The formation of the MTMR6-MTMR9 complex, stabilizes both MTMR6 and MTMR9 protein levels. Plays a role in the late stages of macropinocytosis possibly by regulating MTMR6-mediated dephosphorylation of phosphatidylinositol 3-phosphate in membrane ruffles. Negatively regulates DNA damage-induced apoptosis, in part via its association with MTMR6. Does not bind mono-, di- and tri-phosphorylated phosphatidylinositols, phosphatidic acid and phosphatidylserine. |
| Protein Name | Myotubularin-Related Protein 9Inactive Phosphatidylinositol 3-Phosphatase 9 |
| Database Links | Reactome: R-MMU-1660499 |
| Cellular Localisation | CytoplasmCell ProjectionRuffle MembranePeripheral Membrane ProteinCytoplasmic SidePerinuclear RegionEndoplasmic ReticulumLocalizes To Ruffles During Egf-Induced MacropinocytosisColocalizes With Mtmr6 To The Perinuclear RegionPartially Localizes To The Endoplasmic Reticulum |
| Alternative ELISA Names | Myotubularin-Related Protein 9 ELISA kitInactive Phosphatidylinositol 3-Phosphatase 9 ELISA kitMtmr9 ELISA kitMtmr3 ELISA kit |
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Information sourced from Uniprot.org