Tissue Specificity | |
Post Translational Modifications | N-glycosylated. O-glycosylated.contains chondroitin sulfate. |
Function | Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. |
Protein Name | Macrophage Colony-Stimulating Factor 1Csf-1McsfProteoglycan Macrophage Colony-Stimulating FactorPg-M-Csf Cleaved Into - Processed Macrophage Colony-Stimulating Factor 1 - Macrophage Colony-Stimulating Factor 1 43 Kda Subunit |
Database Links | Reactome: R-MMU-381426Reactome: -MMU-449836Reactome: -MMU-8957275 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinProcessed Macrophage Colony-Stimulating Factor 1: SecretedExtracellular Space |
Alternative ELISA Names | Macrophage Colony-Stimulating Factor 1 ELISA kitCsf-1 ELISA kitMcsf ELISA kitProteoglycan Macrophage Colony-Stimulating Factor ELISA kitPg-M-Csf Cleaved Into - Processed Macrophage Colony-Stimulating Factor 1 - Macrophage Colony-Stimulating Factor 1 43 Kda Subunit ELISA kitCsf1 ELISA kitCsfm ELISA kit |
output | |
Information sourced from Uniprot.org